CG.2.1.11. Thrombin Time (TT) -SISMEX CA600

CG.2.1.11. Thrombin Time (TT)



The plasma thrombin time test measures how quickly a clot forms when a standard amount of bovine thrombin is added to a platelet poor plasma sample from the patient and to a normal plasma control sample. After thrombin is added, the clotting time for each sample is compared with the other and recorded. Because thrombin rapidly converts fibrinogen to a fibrin clot, the test (also known as the thrombin clotting time test) allows a quick but imprecise estimation of plasma fibrinogen levels, which are a function of clotting time.

How the Test is Performed: Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand.

Test  Performed by:  CA600 analyser.

Why the Test is Performed:

·  To detect a fibrinogen deficiency or defect.

·  To help diagnose DIC and hepatic disease.

·  To monitor the effectiveness of heparin or thrombolytic agents.

Normal Results: 11.0 - 17.8  sec. Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

What Abnormal Results Mean:

Prolonged Plasma Thrombin Time

  • Heparin therapy
  • Hepatic disease
  • Disseminated intravascular coagulatio (DIC)
  • Hypofibrinogenemia
  • Dysfibrinogenemia
  • Acute leukemia
  • Lymphoma
  • Factor deficiency
  • Shock

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